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pentobarbital will decrease the extent or impact of amlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.pentobarbital will lower the extent or impact of disopyramide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified.pentobarbital will minimize the extent or result of caripra